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Fig. 6 | Biological Research

Fig. 6

From: LncRNA XIST promotes extracellular matrix synthesis, proliferation and migration by targeting miR-29b-3p/COL1A1 in human skin fibroblasts after thermal injury

Fig. 6

miR-29b-3p abrogation attenuates silence of COL1A1-mediated inhibition of proliferation, migration and ECM synthesis in thermal injured-HSF cells. HSF cells were transfected with si-NC, si-COL1A1, si-COL1A1 and in-miR-NC or in-miR-29b-3p for 24 h and then suffered from thermal injury. COL1A1 protein level (a), ECM synthesis (b), cell proliferation (c) and migration (d) were detected in thermal injured-HSF cells by qRT-PCR, western blot, CCK-8 or trans-well assays. *P < 0.05

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