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Fig. 5 | Biological Research

Fig. 5

From: A novel hydrazide compound exerts anti-metastatic effect against breast cancer

Fig. 5

Compound B inhibits metastasis to the lungs of BALB/c mice inoculated with 4T1 cells. H&E staining was performed on the lungs (a, b). Upon treatment, lungs were sampled to evaluate the extent at which the cells had metastasized. Lung sections were stained with antibody raised against Ki-67 (c, d) and CD31 (e, f), and then with 1,3-diaminobenzidine (DAB) and counterstained with hematoxylin. Representative images of the immunohistochemical analysis are shown. All photomicrographs are at ×400 magnification

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