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Fig. 2 | Biological Research

Fig. 2

From: Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells

Fig. 2

BBR + DDP combination inhibited the expression of PCNA and Ki67. OVCAR3 cells and POCCLs were treated with BBR (100 μM) and/or DDP (5 mg/L) for 24 h. The expression level of Ki67 and PCNA in BBR and/or DDP-treated cells was detected by qRT-PCR (a, c), Western blot (b, d) and immunofluorescence assay (e, f). Data were based on at least three independent experiments, and shown as mean ± SEM. *p < 0.05, **p < 0.01 compared with NC; #p < 0.05, ##p < 0.01 compared with BBR; &p < 0.05, &&p < 0.01 compared with DDP

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