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Fig. 1 | Biological Research

Fig. 1

From: CXCL8(3–72) K11R/G31P protects against sepsis-induced acute kidney injury via NF-κB and JAK2/STAT3 pathway

Fig. 1

Effects of G31P on the renal function and kidney injury of mice. The blood samples of mice were harvested at 6, 12 and 24 h after the colon ligation and puncture, respectively. The levels of SCr (a) and BUN (b) were determined by chromatometry with kits while NGAL (c) and KIM-1 (d) were measured by ELISA. e Renal histological changes in mice were observed by H&E staining (magnification ×200). f The histological score of kidney tissue injury was evaluated by a blinded pathologist. ns represented no significant difference; P < 0.01 versus the levels of biomarkers at 6 h in each group; #P < 0.05, ##P < 0.01 versus the levels of biomarkers at 12 h in each group. G31P: CXCL8(3–72) K11R/G31P; SCr: serum creatinine; BUN: blood urea nitrogen; NGAL: neutrophil gelatinase-associated lipocalin; KIM-1: kidney injury molecule-1

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