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Fig. 5 | Biological Research

Fig. 5

From: MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2

Fig. 5

TUSC2 is involves in the effect of miR-663 in SKOV3 growth and mobility. a The qRT-PCR assay of TUSC2 in SKOV3 cells that co-transfected with TUSC2 over-expression plasmid along with either miR-NC or miR-663. b SKOV3 cells were co-transfected with miR-663 and TUSC2 over-expressing plasmid and the level of TUSC2 was assessed by western blot. c CCK-8 assay shown in the proliferation of SKOV3 cell that co-transfected with miR-663 and TUSC2 over-expression plasmid. d Colony formation analysis of SKOV3 cells co-transfected with miR-663 and TUSC2 over-expressing plasmid. e Wound closure analysis was performed to measure the migration of indicated SKOV3 cells. f Transwell assay was conducted to assess the invasiveness of indicated SKOV3 cells. N = 3, **P < 0.01, compared to miR-NC, ##P < 0.01 in comparison with miR-663 + TUSC2

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