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Fig. 5 | Biological Research

Fig. 5

From: Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways

Fig. 5

mRNA expressions of α-SMA, TIMP-1, Col 1A1, NFATc1 and Wnt 5a in liver tissue. a mRNA expressions of NFATc1, Wnt 5a and fibrosis genes in tissue was measured by qPCR in HBV-infected patients with different liver fibrosis score; *P < 0.05, ϮP < 0.05, P < 0.05, compared with control. b mRNA expressions of NFATc1, Wnt 5a and fibrosis genes in tissue by qPCR in HBV-infected patients with different viral load; *P < 0.05, P < 0.05, compared with control. c NFATc1, pJnk protein expressions in liver tissue was measured by immunohistochemistry and positive index (PI). The relationship between NFATc1, pJnk protein expressions and liver fibrosis was observed by correlation analysis. For NFATc1, r = 0.931, P < 0.05; For pJnk, r = 0.950, P < 0.05. All data presented here were from three independent experiments

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