Fig. 3

Notum inhibited liver fibrosis gene expression in LX-2 cells with HBV exposure. a Cell co-culture model. b LX-2 cells were co-cultured with Hep AD38 cells and transferred with Notum. α-SMA, TIMP-1 and Col 1A1 mRNA expressions in LX-2 cells were measured by qPCR. c, d α-SMA, TIMP-1 and Col 1A1 protein expressions in LX-2 cells were measured by Western-blot. *P < 0.05 compared with mock. All experiments were tried 3 times