Fig. 2

ETV reduced HBV replication and Wnt5a expression in Hep AD38 cells. Cells were treated with ETV at a concentration of 500 nM for 72 h. a HBV DNA level in supernatant was detected by qPCR; b Wnt 5a level in supernatant was detected by ELISA; c HBV X and HBV DNA levels in Hep AD38 cells were detected by qPCR; d Wnt 5a mRNA level in Hep AD38 cells was detected by qPCR; e, f Wnt 5a protein level in Hep AD38 cells was detected by Western-blot. *P < 0.05, ^ϮP < 0.05, ^ǂP < 0.05, compared with 0 h; ^ǂP > 0.05, compared with Ϯ. All data were from three individual experiments