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Table 1 The genes involve in immune responses pathways after FB ingestion

From: Intestinal transcriptional profiling reveals fava bean-induced immune response in DBA/1 mice

Immune response related pathway

GeneID

Inflammatory bowel disease (IBD)

24088, 53791, 21898, 20371

Leukocyte transendothelial migration

13057, 226654, 237038, 57257, 241275, 16409, 14677, 18710, 58187, 216033, 50490, 12737

Complement and coagulation cascades

69864, 78354, 11537, 16409, 12902, 14058, 74145, 14067, 232345

Fc epsilon RI signaling pathway

57257, 18710, 211429, 271844, 102238433

Chemokine signaling pathway

18829, 57257, 100504362, 24047, 14677, 11514, 18710, 245386, 100862177, 65956

Toll-like receptor signaling pathway

24088, 18710, 53791, 21897, 21898, 224419

Toll and Imd signaling pathway

407243, 245381, 224419

B cell receptor signaling pathway

17060, 57257, 18710, 12902

Systemic lupus erythematosus

15077, 319164, 319191, 319167, 319150, 319184

Platelet activation

14677, 11514, 18710, 211429, 271844, 102238433, 27220

IL-17 signaling pathway

14282, 70031, 57890, 224419

Graft-versus-host disease

110557, 15051

NOD-like receptor signaling pathway

13057, 237038, 78688, 21898, 100417831, 381308, 12374, 50490, 224419

Allograft rejection

110557, 15051

Fc gamma R-mediated phagocytosis

111002, 57257, 18710

RIG-I-like receptor signaling pathway

67664, 224419

Natural killer cell mediated cytotoxicity

57257, 18710, 379043, 19368

Cytosolic DNA-sensing pathway

232934, 381308

T cell receptor signaling pathway

57257, 18710, 224419

Rheumatoid arthritis

24088, 21898

Antigen processing and presentation

73442, 110557, 15051

Hematopoietic cell lineage

16409, 12902

Autoimmune thyroid disease

110557, 15051

Th1 and Th2 cell differentiation

67701, 19668

Primary immunodeficiency

17060

Th17 cell differentiation

381538, 20371