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Table 2 Clinicopathological characteristics of patients and their correlation with ErbB1/3 protein expression

From: ErbB1 and ErbB3 co-over expression as a prognostic factor in gastric cancer

  Total ErbB1 p ErbB3 p ErbB1 and ErbB3 p
Over expression Normal Over expression Normal Over expression Normal
Age 96 (40–80)          
Sex     0.313    0.485    0.791
 Male 38 (76%) 19 (50%) 19 (50%)   16 (42.1%) 22 (57.9%)   11 (28.9%) 27 (71.1%)  
 Female 12 (24%) 4 (33.3%) 8 (66.7%)   4 (33.3%) 8 (66.7%)   3 (25%) 9 (75%)  
Size 82 (30–100)          
Location     0.730    0.485    0.797
 Cardia 12 (24%) 5 (41.7%) 7 (58.3%)   4 (33.3%) 8 (66.7%)   3 (25%) 9 (75%)  
 Non-cardia 38 (76%) 18 (47.4%) 20 (52.6%)   16 (42.1%) 22 (57.9%)   11 (28.9%) 27 (71.1%)  
Lauren classification     0.999    0.999    0.550
 Intestinal 47 (94%) 22 (46.8%) 25 (53.2%)   19 (40.4%) 28 (59.6%)   14 (29.8%) 33 (70.2%)  
 Diffuse 3 (6%) 1 (33.3%) 2 (66.7%)   1 (33.3%) 2 (66.7%)   3 (100%)  
Macroscopy     0.028    < 0.05    < 0.05
 Infiltrative 18 (36%) 12 (66.7%) 6 (33.3%)   17 (94.4%) 1 (5.6%)   12 (66.7%) 6 (33.3%)  
 Ulceroinfiltrative 32 (64%) 11 (34.4%) 21 (65.6%)   3 (9.4%) 29 (90.6%)   2 (6.2%) 30 (93.8%)  
Differentiation     0.028    < 0.05    < 0.05
 Poorly 20 (40%) 13 (65%) 7 (35%)   19 (95%) 1 (5%)   13 (65%) 7 (35%)  
 Not-poorly 30 (60%) 10 (33.3%) 20 (66.7%)   1 (3.3%) 29 (96.7%)   1 (3.3%) 29 (96.7%)  
Stage (TNM)     0.027    < 0.05    < 0.05
 I–II 28 (56%) 9 (32.1%) 19 (67.9%)   28 (100%)   28 (100%)  
 III–IV 22 (46%) 14 (63.6%) 8 (36.4%)   20 (90.9%) 2 (9.1%)   14 (63.8%) 8 (36.2%)  
Tumor depth of invasion     0.999    0.254    0.550
 T1–T2 3 (6%) 1 (33.3%) 2 (66.7%)   3 (100%)   3 (100%)  
 T3–T4 47 (94%) 22 (46.8%) 25 (53.2%)   20 (42.6%) 27 (57.4%)   14 (29.8%) 33 (70.2%)  
Lymph node metastasis     0.493    0.503    0.999
 Positive 48 (98%) 23 (47.9%) 25 (52.1%)   20 (41.7%) 28 (58.3%)   14 (29.2%) 34 (70.8%)  
 Negative 2 (2%) 2 (100%)   2 (100%)   2 (100%)  
Recurrence     0.013    < 0.05    < 0.05
 Positive 21 (42%) 14 (66.7%) 7 (33.3%)   20 (95.2%) 1 (4.8%)   14 (66.7%) 7 (33.3%)  
 Negative 29 (58%) 9 (31%) 20 (69%)   29 (100%)   29 (100%)  
  1. Italic values indicate significance of p value (p < 0.05)