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Fig. 3 | Biological Research

Fig. 3

From: Downregulation of TGF-β1 suppressed proliferation and increased chemosensitivity of ovarian cancer cells by promoting BRCA1/Smad3 signaling

Fig. 3

TGF-β1 downregulation suppressed tumor growth of ovarian cancer in a xenograft model. a Photographs of tumor tissues from different groups at day 40 (n = 5). b Growth curves for tumor volumes in xenografts of nude mice were determined based on the tumor volume measured every 3 days from the tenth day for 40 days (n = 5). ***P < 0.001 versus the control group. ###P < 0.001 versus the TGF-β1 overexpression group. c, d Immunohistochemical analysis showing the expression of TGF-β1 in tumor tissues. Data are expressed as the mean ± SD. e–h Western blot showing the expression of TGF-β1, BRCA1, Smad3 and phosphorylated Smad3. Data are expressed as the mean ± SD. ***P < 0.001

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Biological Research

ISSN: 0717-6287

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