Fig. 5
From: MicroRNA-153-3p enhances cell radiosensitivity by targeting BCL2 in human glioma
Restoration of BCL2 expression inhibited miR-153-3p-mediated radiosensitivity of glioma cells. U251 cells with miR-153-3p overexpression were transfected with empty vector or BCL2 vector. a The expression of BCL2 protein was determined using western blot analysis. b After exposure to different doses of IR, MTT assay was used to determine the cell viability. After exposure to 4 Gy IR, cell apoptosis and caspase-3 activity were detected using c, d flow cytometry analysis and e caspase-3 activity assay, respectively. Data represent mean ± SD. *p < 0.05, ***p < 0.001 versus Vector + miR-153-3p