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Fig. 1 | Biological Research

Fig. 1

From: MiR-219-5p inhibits growth and metastasis of ovarian cancer cells by targeting HMGA2

Fig. 1

miR-219-5p suppresses ovarian carcinoma cell proliferation, migration and invasion. a qRT-PCR showing expression of miR-219-5p in SKOV3 cells after treatment with the miR-219-5p mimic, specific inhibitor or scramble (control) for 48 h. Data are expressed as mean ± SD, n = 5. ***P < 0.001 versus scramble. b Measurement of SKOV3 cell proliferation with the CCK-8 assay. Data are expressed as mean ± SD, n = 5. *P < 0.05, ***P < 0.001 versus scramble. ###P < 0.001 versus the mimic group. c, d SKOV3 cell migration and invasion determined using the Transwell® assay after treatment with the miR-219-5p mimic, specific inhibitor or scramble. Data are expressed as mean ± SD, n = 5. ***P < 0.001 versus scramble. ###P < 0.001 versus the mimic group

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