Fig. 3
From: Involvement of K+ATP and Ca2+ channels in hydrogen sulfide-suppressed ageing of porcine oocytes
Effect of the combined treatment with a hydrogen sulfide donor and K+ATP channel inhibitor. Na2S (300 µM, (+)Na2S) was used as the extracellular hydrogen sulfide donor, and glibenclamide (10–100 µM; iKATP) was used to inhibit the K+ATP channel both alone ((−)Na2S) and combined with Na2S ((+)Na2S). A–C The proportions of intact MII oocytes; cell death, including apoptosis or lysis; and parthenogenetically activated oocytes were determined, respectively. Different superscripts indicate statistically significant differences among experimental groups within a treatment (a, b; α, β, γ, δ). Asterisks indicate a significant difference between treatments within the same iKATP concentration (at α level less than 0.01)