Fig. 4

Clinical significance of A-to-I RNA editing in BRCA. a Kaplan-Maier survival proportions for basal-like patients stratified based on ADAR1 mRNA expression levels. Basal-like patients with lower ADAR1 expression are shown in red and Basal-like patients with highest ADAR1 expression are shown in blue, respectively. b Histogram proportion for Basal-like TCGA tumors according to their A to G(I) variant count, showing the Basal-like patients selected for Kaplan-Maier analysis. Basal-like patients with lower ADAR1 expression are shown in red and Basal-like patients with highest ADAR1 expression are shown in blue, respectively. Gauss fit distribution for each subgroup is shown with a continuous line (red or blue accordingly). a Log-rank Mantel-Cox test ** < 0.0192 with a median survival of 90.75 months