Fig. 2
From: Thiamine deficiency contributes to synapse and neural circuit defects
PT induced spine density decrease in vitro. a Increased concentration of pyrithiamine (PT) significantly decreased the dendritic spines density of culturing hippocampal neurons. b Quantification of spine density after the treatment with different concentrations of PT. (N = 3 culture preparations, n = 51, 51, 55, 53 cells numbers; P < 0.0001). All the data are expressed as mean ± SEM from three independent experiments. ***P < 0.0001, one-way ANOVA were used to determine the statistical significance of the differences