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Table 1 Effect of vitamin C and E on serum lipids in SR-B1 KO/ApoER61h/h mice fed with atherogenic diet

From: Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice

Serum lipids Atherogenic diet-fed
SR-BI KO/ApoER61h/h mice
Control
(n = 26)
Vitamin C + E
(n = 24)
p value
Total cholesterol (mg/dL) 1080 ± 292 619 ± 168 < 0.0001
Unesterified cholesterol (UC) (mg/dL) 708 ± 294 354 ± 105 < 0.0001
UC/total cholesterol ratio 0.675 ± 0.30 0.574 ± 0.22 0.1944
Triglycerides (mg/dL) 55 ± 32 28 ± 9 0.0008
Phospholipids (mmol/L) 0.172 ± 0.08 0.097 ± 0.04 0.0003
  1. Values are shown as mean ± standard deviation. Lipids were measured from serum samples obtained 10 days after the beginning of atherogenic diet consumption