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Table 1 Effect of vitamin C and E on serum lipids in SR-B1 KO/ApoER61h/h mice fed with atherogenic diet

From: Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice

Serum lipids

Atherogenic diet-fed

SR-BI KO/ApoER61h/h mice

Control

(n = 26)

Vitamin C + E

(n = 24)

p value

Total cholesterol (mg/dL)

1080 ± 292

619 ± 168

< 0.0001

Unesterified cholesterol (UC) (mg/dL)

708 ± 294

354 ± 105

< 0.0001

UC/total cholesterol ratio

0.675 ± 0.30

0.574 ± 0.22

0.1944

Triglycerides (mg/dL)

55 ± 32

28 ± 9

0.0008

Phospholipids (mmol/L)

0.172 ± 0.08

0.097 ± 0.04

0.0003

  1. Values are shown as mean ± standard deviation. Lipids were measured from serum samples obtained 10 days after the beginning of atherogenic diet consumption
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Biological Research

ISSN: 0717-6287

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