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Table 1 Hypermethylation of various genes investigated in different types of cancers

From: A Nexus model of cellular transition in cancer

S. N.

Site of hypermethylation

Type of cancer

1

Glutathione S transferase gene (GSTPI, also known as GST3)

Prostate and breast cancer [91]

2

Promoter region of Liver Kinase B1 (LKB1)

Papillary breast cancer [92]

3

Promoter region of cyclin-dependent Kinase inhibitor p15INK4B

Leukemia and glioma [93]

4

Promoter CpG island of the O6-MGMT gene

Brain, colon and lung cancer [94]

5

CpG island of death-associated protein Kinase DAP-Kinase

Lymphomas [95]

6

Promoter region of p73 gene

Lymphoma cancer [96]