Fig. 4

Metabolites measured by using 1H-MRS. a The baseline of the 4 groups by using 1H-MRS spectra. b NAA/Cr, Glu/Cr, mI/Cr of the 4 groups were detected before EA treatment. c NAA/Cr, Glu/Cr, mI/Cr of the 4 groups were detected after EA treatment. d NAA/Cr, Glu/Cr, mI/Cr of the 4 groups were detected after EA treatment for 4 weeks. A: WT group, B: APP/PS1 group, C: APP/PS1+DU20 group; D: APP/PS1+NA group. The square represents the detection area. *P < 0.01 versus WT; ^#P < 0.05 versus APP/PS1 group; ^▲P < 0.05 versus APP/PS1+NA group