Fig. 5

In vitro IFNγ and IL4 protein production in wild type and PPARα^−/− mice. Wild type or PPARα^−/− splenic or liver mononuclear cells (MNCs) were isolated from untreated animals and exposed to ConA (1 μg/ml) for 72 h). Protein expression for IFNγ (a) and IL4 (b) were then measured in culture media by ELISA. *p < 0.05 vs. ConA-treated wild type cells. n = 4 experiments