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Fig. 2 | Biological Research

Fig. 2

From: Impaired T cell-mediated hepatitis in peroxisome proliferator activated receptor alpha (PPARα)-deficient mice

Fig. 2

Serum enzyme levels and histopathology from wild type and PPARα−/− deficient mice administered ConA at 15 mg/kg. a Serum alanine aminotransferase (ALT) levels 0, 10 or 24 h following ConA administration in wild type and PPARα−/− mice. b Serum aspartate aminotransferase (AST) levels 0, 10, and 24 h following ConA administration in wild type and PPARα−/− mice. c Hematoxylin and eosin stained liver sections from wild type and PPARα−/− mice 0, 10, and 24 h following ConA administration. Representative ×400 photomicrographs are shown. d Terminal UTP nick-end labeling (TUNEL) staining of liver sections from wild type and PPARα−/− mice 0, 10, and 24 h following ConA administration. Representative ×100 photomicrographs are shown *p < 0.05 vs 0 h wild type value. +p < 0.05 vs. wild type at 10 h post-injection. n = 4 animals per group

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