Table 4 Common BRCA ½ mutation found in multiple Central and South American countries

2

c.68_69delAG

Argentina

✔

Brazil

✔

0.33%

Chile

✔

0.6%

Mexico

✔

Peru

✔

2.6%

5

c.181T>G

Argentina

✔

0.64%

Brazil

✔

Chile

✔

5

c.211A>G

Argentina

✔

1.17%

Brazil

✔

Mexico

✔

✔

Peru

✔

11

c. 798_799delTT

Argentina

✔

Mexico

✔

11

c.815_824dupAGCCATGTGG

Mexico

✔

Peru

✔

11

c.2568T>G

Argentina

✔

Uruguay

✔

11

c.3228_3229delAG

Argentina

✔

Brazil

✔

11

c. 3331_3334delCAAG

Brazil

✔

Chile

✔

0.9%

Colombia

✔

✔

9.4%

1.6%/11.4%^a

11

c. 3858_3861delTGAG

Mexico

✔

✔

Peru

✔

11

c. 3858_3861delTGAG

Chile

✔

Mexico

✔

11

c. 4065_4068delTCAA

Mexico

✔

Peru

✔

13

c.4327>T

Argentina

✔

Mexico

✔

✔

0.25%

18

c. 5123C>A

Argentina

✔

Brazil

✔

Colombia

✔

✔

5.7%

1.3%

Mexico

✔

✔

✔

0.5%

20

c.5266up C

Argentina

✔

Brazil

✔

✔

✔

2.5%/0.65%/5%^a

3.7%

1.2%

Mutation in BRCA 2

 3

c.145G>T

Argentina

✔

Chile

✔

3.7%

Mexico

✔

 11

c.2808_2811 delACAA

Argentina

✔

0.64%

Brazil

✔

✔

Colombia

✔

✔

3.8%

1.3%

Mexico

✔

✔

Peru

✔

0.75%

Venezuela

✔

 11

c.3264d up T

Argentina

✔

Mexico

✔

 11

c.4740_4741insTG

Argentina

✔

Chile

✔

0.6%

 11

c.5351dup A

Argentina

✔

Uruguay

✔

 11

c. 5946delT

Argentina

✔

Brazil

✔

Chile

✔

Costa Rica

✔

 11

c.6024dup G

Argentina

✔

Colombia

✔

Mexico

✔