Fig. 2

CCL2 blockage alleviated TAA-induced microglia activation. Microglia activation in cerebral cortex collected at coma were evaluated through determination of Iba1 expression, a marker of microglia activation, using qRT-PCR (a), western blotting (b) and immunohistochemistry assays (c). The original magnification for immunohistochemical picture was ×200. **P < 0.01, *P < 0.05, vs vehicle; ^## P < 0.01, ^# P < 0.05, vs TAA