TY - JOUR AU - Zhu, J. AU - Yamane, H. AU - Paul, W. E. PY - 2010 DA - 2010// TI - Differentiation of effector CD4 T cell populations (*) JO - Annu Rev Immunol VL - 28 UR - https://doi.org/10.1146/annurev-immunol-030409-101212 DO - 10.1146/annurev-immunol-030409-101212 ID - Zhu2010 ER - TY - JOUR AU - Weaver, C. T. AU - Hatton, R. D. AU - Mangan, P. R. AU - Harrington, L. E. PY - 2007 DA - 2007// TI - IL-17 family cytokines and the expanding diversity of effector T cell lineages JO - Annu Rev Immunol VL - 25 UR - https://doi.org/10.1146/annurev.immunol.25.022106.141557 DO - 10.1146/annurev.immunol.25.022106.141557 ID - Weaver2007 ER - TY - JOUR AU - Luckheeram, R. V. AU - Zhou, R. AU - Verma, A. D. AU - Xia, B. PY - 2012 DA - 2012// TI - CD4(+)T cells: differentiation and functions JO - Clin Dev Immunol VL - 2012 UR - https://doi.org/10.1155/2012/925135 DO - 10.1155/2012/925135 ID - Luckheeram2012 ER - TY - JOUR AU - Tubo, N. J. AU - Jenkins, M. K. PY - 2014 DA - 2014// TI - TCR signal quantity and quality in CD4+ T cell differentiation JO - Trends Immunol VL - 35 UR - https://doi.org/10.1016/j.it.2014.09.008 DO - 10.1016/j.it.2014.09.008 ID - Tubo2014 ER - TY - JOUR AU - Zhu, J. AU - Paul, W. E. PY - 2010 DA - 2010// TI - Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors JO - Immunol Rev VL - 238 UR - https://doi.org/10.1111/j.1600-065X.2010.00951.x DO - 10.1111/j.1600-065X.2010.00951.x ID - Zhu2010 ER - TY - JOUR AU - Gaffen, S. L. PY - 2008 DA - 2008// TI - An overview of IL-17 function and signaling JO - Cytokine VL - 43 UR - https://doi.org/10.1016/j.cyto.2008.07.017 DO - 10.1016/j.cyto.2008.07.017 ID - Gaffen2008 ER - TY - JOUR AU - Zambrano-Zaragoza, J. F. AU - Romo-Martinez, E. J. AU - Duran-Avelar Mde, J. AU - Garcia-Magallanes, N. AU - Vibanco-Perez, N. PY - 2014 DA - 2014// TI - Th17 cells in autoimmune and infectious diseases JO - Int J Inflam VL - 2014 UR - https://doi.org/10.1155/2014/651503 DO - 10.1155/2014/651503 ID - Zambrano-Zaragoza2014 ER - TY - JOUR AU - Damsker, J. M. AU - Hansen, A. M. AU - Caspi, R. R. PY - 2010 DA - 2010// TI - Th1 and Th17 cells: adversaries and collaborators JO - Ann NY Acad Sci VL - 1183 UR - https://doi.org/10.1111/j.1749-6632.2009.05133.x DO - 10.1111/j.1749-6632.2009.05133.x ID - Damsker2010 ER - TY - JOUR AU - Lovett-Racke, A. E. AU - Yang, Y. AU - Racke, M. K. PY - 2011 DA - 2011// TI - Th1 versus Th17: are T cell cytokines relevant in multiple sclerosis? JO - Biochim Biophys Acta VL - 1812 UR - https://doi.org/10.1016/j.bbadis.2010.05.012 DO - 10.1016/j.bbadis.2010.05.012 ID - Lovett-Racke2011 ER - TY - JOUR AU - Wang, Z. AU - Qiu, J. AU - Guo, T. B. AU - Liu, A. AU - Wang, Y. AU - Li, Y. AU - Zhang, J. Z. PY - 2007 DA - 2007// TI - Anti-inflammatory properties and regulatory mechanism of a novel derivative of artemisinin in experimental autoimmune encephalomyelitis JO - J Immunol VL - 179 UR - https://doi.org/10.4049/jimmunol.179.9.5958 DO - 10.4049/jimmunol.179.9.5958 ID - Wang2007 ER - TY - JOUR AU - Noseworthy, J. H. AU - Lucchinetti, C. AU - Rodriguez, M. AU - Weinshenker, B. G. PY - 2000 DA - 2000// TI - Multiple sclerosis JO - N Engl J Med VL - 343 UR - https://doi.org/10.1056/NEJM200009283431307 DO - 10.1056/NEJM200009283431307 ID - Noseworthy2000 ER - TY - JOUR AU - Goverman, J. PY - 2009 DA - 2009// TI - Autoimmune T cell responses in the central nervous system JO - Nat Rev Immunol VL - 9 UR - https://doi.org/10.1038/nri2550 DO - 10.1038/nri2550 ID - Goverman2009 ER - TY - JOUR AU - Skundric, D. S. PY - 2005 DA - 2005// TI - Experimental models of relapsing-remitting multiple sclerosis: current concepts and perspective JO - Curr Neurovasc Res VL - 2 UR - https://doi.org/10.2174/156720205774322601 DO - 10.2174/156720205774322601 ID - Skundric2005 ER - TY - JOUR AU - Paris, D. AU - Beaulieu-Abdelahad, D. AU - Mullan, M. AU - Ait-Ghezala, G. AU - Mathura, V. AU - Bachmeier, C. AU - Crawford, F. AU - Mullan, M. J. PY - 2013 DA - 2013// TI - Amelioration of experimental autoimmune encephalomyelitis by anatabine JO - PLoS ONE VL - 8 UR - https://doi.org/10.1371/journal.pone.0055392 DO - 10.1371/journal.pone.0055392 ID - Paris2013 ER - TY - JOUR AU - Prat, A. AU - Antel, J. PY - 2005 DA - 2005// TI - Pathogenesis of multiple sclerosis JO - Curr Opin Neurol VL - 18 UR - https://doi.org/10.1097/01.wco.0000169737.99040.31 DO - 10.1097/01.wco.0000169737.99040.31 ID - Prat2005 ER - TY - JOUR AU - Chang, J. H. AU - Cha, H. R. AU - Lee, D. S. AU - Seo, K. Y. AU - Kweon, M. N. PY - 2010 DA - 2010// TI - 1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis JO - PLoS ONE VL - 5 UR - https://doi.org/10.1371/journal.pone.0012925 DO - 10.1371/journal.pone.0012925 ID - Chang2010 ER - TY - JOUR AU - Ebers, G. C. PY - 2008 DA - 2008// TI - Environmental factors and multiple sclerosis JO - Lancet Neurol VL - 7 UR - https://doi.org/10.1016/S1474-4422(08)70042-5 DO - 10.1016/S1474-4422(08)70042-5 ID - Ebers2008 ER - TY - JOUR AU - Ferber, I. A. AU - Brocke, S. AU - Taylor-Edwards, C. AU - Ridgway, W. AU - Dinisco, C. AU - Steinman, L. AU - Dalton, D. AU - Fathman, C. G. PY - 1996 DA - 1996// TI - Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE) JO - J Immunol VL - 156 ID - Ferber1996 ER - TY - JOUR AU - Kebir, H. AU - Kreymborg, K. AU - Ifergan, I. AU - Dodelet-Devillers, A. AU - Cayrol, R. AU - Bernard, M. AU - Giuliani, F. AU - Arbour, N. AU - Becher, B. AU - Prat, A. PY - 2007 DA - 2007// TI - Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation JO - Nat Med VL - 13 UR - https://doi.org/10.1038/nm1651 DO - 10.1038/nm1651 ID - Kebir2007 ER - TY - JOUR AU - Prat, A. AU - Biernacki, K. AU - Antel, J. P. PY - 2005 DA - 2005// TI - Th1 and Th2 lymphocyte migration across the human BBB is specifically regulated by interferon beta and copolymer-1 JO - J Autoimmun VL - 24 UR - https://doi.org/10.1016/j.jaut.2005.01.004 DO - 10.1016/j.jaut.2005.01.004 ID - Prat2005 ER - TY - JOUR AU - Domingues, H. S. AU - Mues, M. AU - Lassmann, H. AU - Wekerle, H. AU - Krishnamoorthy, G. PY - 2010 DA - 2010// TI - Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis JO - PLoS ONE VL - 5 UR - https://doi.org/10.1371/journal.pone.0015531 DO - 10.1371/journal.pone.0015531 ID - Domingues2010 ER - TY - JOUR AU - Korn, T. AU - Oukka, M. AU - Kuchroo, V. AU - Bettelli, E. PY - 2007 DA - 2007// TI - Th17 cells: effector T cells with inflammatory properties JO - Semin Immunol VL - 19 UR - https://doi.org/10.1016/j.smim.2007.10.007 DO - 10.1016/j.smim.2007.10.007 ID - Korn2007 ER - TY - JOUR AU - Toh, M. -. L. AU - Miossec, P. PY - 2007 DA - 2007// TI - The role of T cells in rheumatoid arthritis: new subsets and new targets JO - Curr Opin Rheumatol VL - 19 UR - https://doi.org/10.1097/BOR.0b013e32805e87e0 DO - 10.1097/BOR.0b013e32805e87e0 ID - Toh2007 ER - TY - JOUR AU - Martinelli, V. AU - Radaelli, M. AU - Straffi, L. AU - Rodegher, M. AU - Comi, G. PY - 2009 DA - 2009// TI - Mitoxantrone: benefits and risks in multiple sclerosis patients JO - Neurol Sci VL - 30 UR - https://doi.org/10.1007/s10072-009-0142-7 DO - 10.1007/s10072-009-0142-7 ID - Martinelli2009 ER - TY - JOUR AU - Rinaldi, F. AU - Perini, P. AU - Calabrese, M. AU - Rinaldi, L. AU - Gallo, P. PY - 2009 DA - 2009// TI - Severe relapses after the first infusion of natalizumab in active relapsing-remitting multiple sclerosis JO - Mult Scler VL - 15 UR - https://doi.org/10.1177/1352458509107011 DO - 10.1177/1352458509107011 ID - Rinaldi2009 ER - TY - JOUR AU - Lugaresi, A. AU - Ioia, M. AU - Travaglini, D. AU - Pietrolongo, E. AU - Pucci, E. AU - Onofrj, M. PY - 2013 DA - 2013// TI - Risk-benefit considerations in the treatment of relapsing-remitting multiple sclerosis JO - Neuropsychiatric Dis Treat VL - 9 UR - https://doi.org/10.2147/NDT.S45144 DO - 10.2147/NDT.S45144 ID - Lugaresi2013 ER - TY - STD TI - Wingerchuk DM, Carter JL. Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies. In: Mayo Clinic Proceedings. Amsterdam: Elsevier; 2014. p. 225–40. ID - ref27 ER - TY - JOUR AU - Kim, D. G. AU - Kang, Y. AU - Lee, H. AU - Lee, E. K. AU - Nam, T. G. AU - Kim, J. A. AU - Jeong, B. S. PY - 2014 DA - 2014// TI - 6-Amino-2,4,5-trimethylpyridin-3-ols: a new general synthetic route and antiangiogenic activity JO - Eur J Med Chem VL - 78 UR - https://doi.org/10.1016/j.ejmech.2014.03.045 DO - 10.1016/j.ejmech.2014.03.045 ID - Kim2014 ER - TY - JOUR AU - Banskota, S. AU - Gautam, J. AU - Regmi, S. C. AU - Gurung, P. AU - Park, M. H. AU - Kim, S. J. AU - Nam, T. G. AU - Jeong, B. S. AU - Kim, J. A. PY - 2016 DA - 2016// TI - BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, inhibits serotonin-induced angiogenesis and tumor growth through PI3K/NOX pathway JO - PLoS ONE VL - 11 UR - https://doi.org/10.1371/journal.pone.0148133 DO - 10.1371/journal.pone.0148133 ID - Banskota2016 ER - TY - JOUR AU - Khansari, N. AU - Shakiba, Y. AU - Mahmoudi, M. PY - 2009 DA - 2009// TI - Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer JO - Recent Pat Inflamm Allergy Drug Discov VL - 3 UR - https://doi.org/10.2174/187221309787158371 DO - 10.2174/187221309787158371 ID - Khansari2009 ER - TY - JOUR AU - Omata, Y. AU - Saito, Y. AU - Yoshida, Y. AU - Jeong, B. S. AU - Serwa, R. AU - Nam, T. G. AU - Porter, N. A. AU - Niki, E. PY - 2010 DA - 2010// TI - Action of 6-amino-3-pyridinols as novel antioxidants against free radicals and oxidative stress in solution, plasma, and cultured cells JO - Free Radic Biol Med VL - 48 UR - https://doi.org/10.1016/j.freeradbiomed.2010.02.018 DO - 10.1016/j.freeradbiomed.2010.02.018 ID - Omata2010 ER - TY - JOUR AU - Serwa, R. AU - Nam, T. G. AU - Valgimigli, L. AU - Culbertson, S. AU - Rector, C. L. AU - Jeong, B. S. AU - Pratt, D. A. AU - Porter, N. A. PY - 2010 DA - 2010// TI - Preparation and investigation of vitamin B6-derived aminopyridinol antioxidants JO - Chemistry VL - 16 UR - https://doi.org/10.1002/chem.201001382 DO - 10.1002/chem.201001382 ID - Serwa2010 ER - TY - JOUR AU - Timilshina, M. AU - Kang, Y. AU - Dahal, I. AU - You, Z. AU - Nam, T. AU - Jeong, B. AU - Kim, K. AU - Chang, J. PY - 2016 DA - 2016// TI - BJ-3105, a 6- Alkoxypyridin-3-ol Analog, impairs T Cell differentiation and prevents experimental autoimmune encephalomyelitis disease progression JO - PLoS ONE ID - Timilshina2016 ER - TY - JOUR AU - Wan, Y. Y. AU - Flavell, R. A. PY - 2009 DA - 2009// TI - How diverse—CD4 effector T cells and their functions JO - J Mol Cell Biol VL - 1 UR - https://doi.org/10.1093/jmcb/mjp001 DO - 10.1093/jmcb/mjp001 ID - Wan2009 ER - TY - JOUR AU - Zhao, Y. G. AU - Wang, Y. AU - Guo, Z. AU - Dan, H. C. AU - Baldwin, A. S. AU - Hao, W. AU - Wan, Y. Y. PY - 2012 DA - 2012// TI - Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway JO - J Immunol VL - 189 UR - https://doi.org/10.4049/jimmunol.1200919 DO - 10.4049/jimmunol.1200919 ID - Zhao2012 ER - TY - JOUR AU - Lovett-Racke, A. E. AU - Yang, Y. AU - Racke, M. K. PY - 2011 DA - 2011// TI - Th1 versus Th17: are T cell cytokines relevant in multiple sclerosis? JO - Biochimica Biophysica Acta. VL - 1812 UR - https://doi.org/10.1016/j.bbadis.2010.05.012 DO - 10.1016/j.bbadis.2010.05.012 ID - Lovett-Racke2011 ER - TY - JOUR AU - Barnden, M. J. AU - Allison, J. AU - Heath, W. R. AU - Carbone, F. R. PY - 1998 DA - 1998// TI - Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements JO - Immunol Cell Biol VL - 76 UR - https://doi.org/10.1046/j.1440-1711.1998.00709.x DO - 10.1046/j.1440-1711.1998.00709.x ID - Barnden1998 ER - TY - JOUR AU - Reboldi, A. AU - Coisne, C. AU - Baumjohann, D. AU - Benvenuto, F. AU - Bottinelli, D. AU - Lira, S. AU - Uccelli, A. AU - Lanzavecchia, A. AU - Engelhardt, B. AU - Sallusto, F. PY - 2009 DA - 2009// TI - CC chemokine receptor 6—regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE JO - Nat Immunol VL - 10 UR - https://doi.org/10.1038/ni.1716 DO - 10.1038/ni.1716 ID - Reboldi2009 ER - TY - JOUR AU - Stromnes, I. M. AU - Cerretti, L. M. AU - Liggitt, D. AU - Harris, R. A. AU - Goverman, J. M. PY - 2008 DA - 2008// TI - Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells JO - Nat Med VL - 14 UR - https://doi.org/10.1038/nm1715 DO - 10.1038/nm1715 ID - Stromnes2008 ER - TY - JOUR AU - Ciraci, C. AU - Janczy, J. R. AU - Jain, N. AU - Haasken, S. AU - e Silva, C. P. AU - Benjamim, C. F. AU - Sadler, J. J. AU - Olivier, A. K. AU - Iwakura, Y. AU - Shayakhmetov, D. M. PY - 2016 DA - 2016// TI - Immune complexes indirectly suppress the generation of Th17 responses in vivo JO - PLoS ONE VL - 11 UR - https://doi.org/10.1371/journal.pone.0151252 DO - 10.1371/journal.pone.0151252 ID - Ciraci2016 ER - TY - JOUR AU - Sospedra, M. AU - Martin, R. PY - 2005 DA - 2005// TI - Immunology of multiple sclerosis JO - Annu Rev Immunol VL - 23 UR - https://doi.org/10.1146/annurev.immunol.23.021704.115707 DO - 10.1146/annurev.immunol.23.021704.115707 ID - Sospedra2005 ER - TY - JOUR AU - Mosmann, T. R. AU - Coffman, R. L. PY - 1989 DA - 1989// TI - TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties JO - Annu Rev Immunol VL - 7 UR - https://doi.org/10.1146/annurev.iy.07.040189.001045 DO - 10.1146/annurev.iy.07.040189.001045 ID - Mosmann1989 ER - TY - JOUR AU - Kuchroo, V. K. AU - Anderson, A. C. AU - Waldner, H. AU - Munder, M. AU - Bettelli, E. AU - Nicholson, L. B. PY - 2002 DA - 2002// TI - T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire JO - Annu Rev Immunol VL - 20 UR - https://doi.org/10.1146/annurev.immunol.20.081701.141316 DO - 10.1146/annurev.immunol.20.081701.141316 ID - Kuchroo2002 ER - TY - JOUR AU - Dardalhon, V. AU - Korn, T. AU - Kuchroo, V. K. AU - Anderson, A. C. PY - 2008 DA - 2008// TI - Role of Th1 and Th17 cells in organ-specific autoimmunity JO - J Autoimmun VL - 31 UR - https://doi.org/10.1016/j.jaut.2008.04.017 DO - 10.1016/j.jaut.2008.04.017 ID - Dardalhon2008 ER - TY - JOUR AU - El-behi, M. AU - Rostami, A. AU - Ciric, B. PY - 2010 DA - 2010// TI - Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis JO - J Neuroimmune Pharmacol VL - 5 UR - https://doi.org/10.1007/s11481-009-9188-9 DO - 10.1007/s11481-009-9188-9 ID - El-behi2010 ER - TY - JOUR AU - Chastain, E. M. AU - D’Anne, S. D. AU - Rodgers, J. M. AU - Miller, S. D. PY - 2011 DA - 2011// TI - The role of antigen presenting cells in multiple sclerosis JO - Biochimica Biophysica Acta. VL - 1812 UR - https://doi.org/10.1016/j.bbadis.2010.07.008 DO - 10.1016/j.bbadis.2010.07.008 ID - Chastain2011 ER - TY - JOUR AU - Bailey, S. R. AU - Nelson, M. H. AU - Himes, R. A. AU - Li, Z. AU - Mehrotra, S. AU - Paulos, C. M. PY - 2014 DA - 2014// TI - Th17 cells in cancer: the ultimate identity crisis JO - Front Immunol VL - 5 UR - https://doi.org/10.3389/fimmu.2014.00276 DO - 10.3389/fimmu.2014.00276 ID - Bailey2014 ER - TY - JOUR AU - Belikov, A. V. AU - Schraven, B. AU - Simeoni, L. PY - 2015 DA - 2015// TI - T cells and reactive oxygen species JO - J Biomed Sci VL - 22 UR - https://doi.org/10.1186/s12929-015-0194-3 DO - 10.1186/s12929-015-0194-3 ID - Belikov2015 ER - TY - JOUR AU - Chen, X. AU - Song, M. AU - Zhang, B. AU - Zhang, Y. PY - 2016 DA - 2016// TI - Reactive oxygen species regulate T cell immune response in the tumor microenvironment JO - Oxid Med Cell Longev. VL - 2016 ID - Chen2016 ER - TY - JOUR AU - Wei, J. AU - Zhang, M. AU - Zhou, J. PY - 2015 DA - 2015// TI - Myeloid-derived suppressor cells in major depression patients suppress T-cell responses through the production of reactive oxygen species JO - Psychiatry Res VL - 228 UR - https://doi.org/10.1016/j.psychres.2015.06.002 DO - 10.1016/j.psychres.2015.06.002 ID - Wei2015 ER - TY - JOUR AU - Bonini, M. G. AU - Malik, A. B. PY - 2014 DA - 2014// TI - Regulating the regulator of ROS production JO - Cell Res VL - 24 UR - https://doi.org/10.1038/cr.2014.66 DO - 10.1038/cr.2014.66 ID - Bonini2014 ER -