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Table 2 Biologic pathways enriched by differentially expressed microRNAs

From: Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney

KEGG class KEGG description Odds ratio P value Genes Num
Environmental information processing AMPK signaling pathway 2.22 0.008184 14
Jak-STAT signaling pathway 2.12 0.009269 15
FoxO signaling pathway 2.09 0.01286 14
Cell adhesion molecules (CAMs) 2.02 0.013299 15
ErbB signaling pathway 2.35 0.016766 10
Cytokine-cytokine receptor interaction 1.63 0.03407 20
PI3K-Akt signaling pathway 1.52 0.036417 26
ECM-receptor interaction 2.02 0.046688 9
Genetic information processing Fanconi anemia pathway 2.53 0.042796 6
Human diseases Choline metabolism in cancer 2.41 0.007808 12
Pancreatic cancer 2.82 0.008459 9
Renal cell carcinoma 2.82 0.008459 9
Glioma 2.50 0.0227 8
Non-small cell lung cancer 2.59 0.027265 7
Measles 1.84 0.042725 12
Type II diabetes mellitus 2.53 0.042796 6
Proteoglycans in cancer 1.65 0.042942 17
Metabolism Valine, leucine and isoleucine degradation 3.10 0.007801 8
Lysine degradation 2.83 0.01867 7
beta-Alanine metabolism 3.41 0.023687 5
Glycosphingolipid biosynthesis—lacto and neolacto series 3.37 0.0429 4
Glycosphingolipid biosynthesis—globo series 4.41 0.043669 3
Organismal systems Fc epsilon RI signaling pathway 2.67 0.011246 9
Osteoclast differentiation 1.95 0.031094 12
Neurotrophin signaling pathway 1.95 0.031094 12
Cholinergic synapse 2.00 0.032356 11
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