Table 2 Biologic pathways enriched by differentially expressed microRNAs
From: Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney
KEGG class | KEGG description | Odds ratio | P value | Genes Num |
|---|---|---|---|---|
Environmental information processing | AMPK signaling pathway | 2.22 | 0.008184 | 14 |
Jak-STAT signaling pathway | 2.12 | 0.009269 | 15 | |
FoxO signaling pathway | 2.09 | 0.01286 | 14 | |
Cell adhesion molecules (CAMs) | 2.02 | 0.013299 | 15 | |
ErbB signaling pathway | 2.35 | 0.016766 | 10 | |
Cytokine-cytokine receptor interaction | 1.63 | 0.03407 | 20 | |
PI3K-Akt signaling pathway | 1.52 | 0.036417 | 26 | |
ECM-receptor interaction | 2.02 | 0.046688 | 9 | |
Genetic information processing | Fanconi anemia pathway | 2.53 | 0.042796 | 6 |
Human diseases | Choline metabolism in cancer | 2.41 | 0.007808 | 12 |
Pancreatic cancer | 2.82 | 0.008459 | 9 | |
Renal cell carcinoma | 2.82 | 0.008459 | 9 | |
Glioma | 2.50 | 0.0227 | 8 | |
Non-small cell lung cancer | 2.59 | 0.027265 | 7 | |
Measles | 1.84 | 0.042725 | 12 | |
Type II diabetes mellitus | 2.53 | 0.042796 | 6 | |
Proteoglycans in cancer | 1.65 | 0.042942 | 17 | |
Metabolism | Valine, leucine and isoleucine degradation | 3.10 | 0.007801 | 8 |
Lysine degradation | 2.83 | 0.01867 | 7 | |
beta-Alanine metabolism | 3.41 | 0.023687 | 5 | |
Glycosphingolipid biosynthesis—lacto and neolacto series | 3.37 | 0.0429 | 4 | |
Glycosphingolipid biosynthesis—globo series | 4.41 | 0.043669 | 3 | |
Organismal systems | Fc epsilon RI signaling pathway | 2.67 | 0.011246 | 9 |
Osteoclast differentiation | 1.95 | 0.031094 | 12 | |
Neurotrophin signaling pathway | 1.95 | 0.031094 | 12 | |
Cholinergic synapse | 2.00 | 0.032356 | 11 |