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Table 3 Copy numbers of allele and loss of heterozygosity (LOH) for the genes using the allele-specific copy number (ASCN) analysis

From: Analysis of gene expression changes associated with human carcinoma-associated fibroblasts in non-small cell lung carcinoma

Gene symbol The copy number of A allele The copy number of B allele Proportion (%) Description Log2 FC
TGFB3 1.7 0.3 70 Copy neutral LOH in 70% −0.96
SPHK1 0.3 1.7 70 Copy neutral LOH in 70% 0.6825
NTS 0.5 1.5 50 Copy neutral LOH in 50% −0.7975
CXCL10 1.5 0.5 50 Copy neutral LOH in 50% 0.66
F2RL1 0.5 1.5 50 Copy neutral LOH in 50% −1.375
TGFBI 0.6 1.4 40 Loss of one allele in 40% −1.23
COL3A1 1.4 0.6 40 Loss of one allele in 50% −1.12
LUM 1.2 0.8 20 Loss of one allele in 20% −0.665
IGF2 0.8 1.2 20 Loss of one allele in 20% 1.07125
GNG2 0.9 1.1 10 Imbalance in 10% −1.3775
COL14A1 1.1 0.9 10 Imbalance in 10% −1.8125
WNT2 1.1 1 5 Imbalance in 5% −1.1275
MGP 1 1 0 Expected balance −2.3075
BMP4 1 1 0 Expected balance −1.115
PPARG 1 1 0 Expected balance −1.1
TLR4 1 1 0 Expected balance 1.09
  1. Gene symbol the name of one gene, proportion the percentage of copy number of A allele minus copy number of B allele, Description the frequency of LOH, FC fold change
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