Fig. 3
From: Uptake of DNA by cancer cells without a transfection reagent
Uptake of AFP DNA or genomic DNA by HCC cells, and uptake of ISONA by different cell liners. a Both ISONA150 and genomic DNAs can be taken up efficiently by Huh7 but not by THLE-3 cells. The uptake was significant as early as 10 min after DNA was added. b Uptake of DNA fragments was compared with single nucleotide, it is size dependent and unlikely to be taken up when the size is over 6.7 kb. c ISONA compounds were incubated with different cell lines overnight, uptake was significant in breast cancer, lung cancer and liver cancer cells. The uptake is minimal in noncancerous cells