Fig. 6
From: In vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells
Annexin V-FITC and PI staining showing apoptosis induction. Flow cytometry using annexin V-FITC and PI staining of cells propagated in growth medium (a), 0.024% vehicle-treated control (b), 180 nM ESE-15-ol-treated cells (c) and 1 μM 2ME2-treated cells (d). Exposure to ESE-15-ol and 2ME2 resulted in significant loss of viability (P < 0.05). ESE-15-ol-treated cells presented with 25% viable cells, 41% early apoptotic cells, 15% late apoptotic cells and 19% necrotic cells. 2ME2-treated cells presented with 48% viable cells, 26% early apoptotic cells, 15% late apoptotic cells and 11% necrotic cells