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Table 6 Patterns of four amino acids

From: 50 years of amino acid hydrophobicity scales: revisiting the capacity for peptide classification

Sequence pool

Peptide

FO in pool

Average FO in remaining set

Average FO in remaining set GBSS

dc-helix

ALAA

0.0005088

0.0001336

0.0001327

AALA

0.0004970

0.0001545

0.0001559

ALLE

0.0003787

6.55e−05

6.82e−05

dc-random

GSSG

0.0028090

0.0002055

0.0001760

SSGS

0.0015990

0.0001405

0.0001205

SGSS

0.0014350

0.0001022

7.90e−05

HHHH

0.0007792

4.17e−05

2.41e−05

EEEE

0.0003691

2.28e−05

1.88e−05

dc-sheet

VLLV

0.0003481

0.0001082

0.0001198

dd-helix

EELL*

0.0003622

5.37e−05

5.67e−05

LEEL*

0.0003372

6.47e−05

6.58e−05

dd-random

GSSG

0.0006914

0.0003379

0.0003685

SSGS

0.0003872

0.0002163

0.0002307

SGSS

0.0003042

0.0001729

0.0001818

SSGL

0.0002489

4.35e−05

4.62e−05

dd-sheet

GEVV*

0.0002647

4.57e−05

4.93e−05

PDGT*

0.0002427

1.19e−05

1.53e−05

DGSV*

0.0002427

2.88e−05

3.05e−05

no-helix

SGSS

0.0001950

0.0001797

0.0001918

PDGS

0.0001509

2.59e−05

3.24e−05

no-random

VVGI

0.0017010

4.14e−05

3.84e−05

QELD

0.0010210

1.13e05

1.45e05

no-sheet

LEAL

0.0003080

8.56e−05

9.38e−05

random

GSSG*

0.0012510

0.0003029

2.53e−05

GPSS

0.0007403

0.0001942

4.57e−05

SGPS

0.0006586

0.0001508

2.70e−05

SSGS

0.0005360

1.43e−05

6.00e07

SGSS

0.0005156

1.14e−05

3.60e06

s-sheet

VKVI

0.0001704

2.9e−06

1.16e−05

krtm-helix

LGLL

0.0012460

6.78e−05

5.58e−05

VLLV

0.0009341

7.16e−05

6.66e−05

GIAL

0.0009341

5.29e−05

4.11e−05

tm-helix

LLLL

0.0004439

7.87e−05

4.07e−05

LILL

0.0004040

3.21e−05

1.25e−05

LLLV

0.0003990

4.38e−05

2.15e−05

ILLL

0.0003891

2.98e−05

1.73e−05

krtm-sheet

SIGA

0.0012020

2.92e−05

1.69e05

tm-sheet

SGPL

0.0004559

1.88e−05

1.20e−05

SLNL

0.0004079

1.96e−05

2.15e−05

LYGG

0.0004079

1.06e−05

9.80e−06

  1. Given are the sequence pool name (column 1) and peptide sequence with the highest frequency of occurrence (column 2); the frequency of occurrence (FO) of this peptide in the according pool (column 3), the frequency of occurrence of this peptide in the pool containing all sequences except the one of the analyzed pool (column 4), the frequency of occurrence of this peptide in the pool containing all sequences generated by the same strategy (GBSS) as the analyzed pool excluding the sequences of the analyzed pool (column 5). Italic shows peptides that have an at least 50-fold higher frequency, with respect to the remaining sets (column 4) or the remaining peptides generated by the same strategy (column 5). Peptide sequences with p values below 0.05 were marked by an asterisk