Table 3 GPx polymorphism and parameter stratification by CHD status

Age (years)

60.63 ± 12.27

62.98 ± 11.89

0.07

Body mass index (kg/m²)

24.73 ± 3.52

28.05 ± 3.17

<10 ⁻⁴

Male, n (%)

119 (58.62 %)

97 (59.15 %)

0.92

Hypertension, n (%)

13 (6.40 %)

96 (58.54 %)

<10 ⁻⁴

Diabetes mellitus, n (%)

10 (4.93 %)

59 (35.98 %)

<10 ⁻⁴

Plasma glucose (mmol/l)

4.33 ± 0.71

4.47 ± 2.91

0.51

LDL cholesterol (mmol/l)

2.54 ± 1.12

3.28 ± 1.13

<10 ⁻⁴

HDL cholesterol (mmol/l)

0.83 ± 0.37

0.82 ± 0.27

0.77

Triglycerides (mmol/l)

1.24 ± 0.64

1.31 ± 0.77

0.34

Non enzymatic antioxidant parameters

 Uric Acid (µmol/l)

312.96 ± 92.00

335.82 ± 147.99

0.07

 Total bilirubin (µmol/l)

17.04 ± 4.73

7.68 ± 4.81

<10 ⁻⁴

 Direct bilirubin (µmol/l)

7.34 ± 3.21

2.36 ± 1.08

<10 ⁻⁴

 Albumin (g/l)

41.74 ± 6.05

40.78 ± 4.18

0.09

 Iron (µmol/l)

18.23 ± 4.94

16.38 ± 3.47

<10 ⁻⁴

Enzymatic antioxidant parameters

 GPx activity, (U/gHb)

42.17 ± 13.99

40.20 ± 12.25

0.16

 TAS (mmol/l)

1.68 ± 0.26

1.37 ± 0.25

<10 ⁻⁴

 GPx genotypes (%), n (CC/CT/TT)

43.84/44.34/11.82 %

55.49/37.80/6.71 %

0.051

89/90/24

91/62/11

0.1

 GPx genotypes (%), n (CC + CT/TT)

88.18/11.82 %

93.29/6.71

179/24

153/11