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Table 2 Basic characteristics of the control and case groups by gender

From: MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity

Trait Males (N = 216) Females (N = 151)
Controls (N = 119) Cases (N = 97) P Controls (N = 84) Cases (N = 67) P
Age (years) 58.68 ± 12.01 64.15 ± 10.71 <10 −4 63.38 ± 12.16 61.28 ± 11.00 0.27
Body mass index (kg/m2) 24.80 ± 3.41 25.23 ± 2.79 0.32 25.64 ± 3.68 24.93 ± 3.66 0.24
Hypertension, n (%) 0 (0.0 %) 65 (67.01 %) <10 −4 13 (15.48 %) 18 (26.87 %) 0.09
Diabetes mellitus, n (%) 0 (0.0 %) 39 (58.21 %) <10 −4 10 (11.90 %) 20 (29.85 %) 0.006
Plasma glucose (mmol/l) 4.56 ± 0.71 5.02 ± 3.09 0.12 4.37 ± 0.70 4.71 ± 2.13 0.17
LDL cholesterol (mmol/l) 2.55 ± 1.24 3.13 ± 1.14 5E−04 2.54 ± 1.14 3.49 ± 1.49 <10 −4
Triglycerides (mmol/l) 1.24 ± 0.73 1.21 ± 0.65 0.75 1.33 ± 0.47 1.47 ± 0.92 0.23
HDL cholesterol (mmol/l) 0.83 ± 0.22 0.84 ± 0.27 0.76 0.82 ± 0.44 0.79 ± 0.26 0.62
Non enzymatic antioxidant parameters
 Uric Acid (µmol/l) 332.3 ± 92.90 342.38 ± 154.27 0.55 285.21 ± 83.71 326.27 ± 138.95 0.03
 Total bilirubin (µmol/l) 18.39 ± 4.21 8.11 ± 4.58 <10 −4 15.89 ± 5.49 7.62 ± 5.04 <10 −4
 Direct bilirubin (µmol/l) 7.93 ± 3.14 2.71 ± 1.95 <10 −4 6.83 ± 3.72 2.07 ± 1.74 <10 −4
 Albumin (g/l) 41.72 ± 4.23 40.65 ± 4.30 0.07 41.75 ± 7.83 40.95 ± 4.10 0.45
 Iron (µmol/l) 18.47 ± 4.54 16.20 ± 3.90 10 −4 17.93 ± 5.41 16.60 ± 3.10 0.075
Enzymatic antioxidant parameters
 SOD activity, (U/gHb) 1321.4 ± 204.8 1089.2 ± 219.7 <10 −4 1463.8 ± 233.4 1166.5 ± 213.9 <10 −4
 TAS (mmol/l) 1.63 ± 0.271 1.40 ± 0.232 <10 −4 1.70 ± 0.267 1.38 ± 0.289 <10 −4
 SOD genotypes (%), n (CC/CT/TT) 31.93/45.38/22.69 % 23.71/37.11/39.18 % 0.03 17.86/55.95/26.19 % 23.88/52.24/23.88 % 0.66
38/54/27 23/36/38   15/47/22 16/35/16  
  1. *P < 0.05 was required for statistical significance