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Table 1 Basic characteristics of the study population by genotype

From: MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity

Trait SOD genotype GPx genotype
Ala/Ala (CC) (N = 92) Ala/Val (CT) (N = 172) Val/Val (TT) (N = 103) P Pro/Pro (CC) (N = 180) Pro/Leu (CC) (N = 152) Leu/Leu (TT) (N = 35) P
Age (years) 60.47 ± 10.88 62.42 ± 11.98 61.51 ± 11.99 0.43 61.57 ± 11.59 62.42 ± 12.24 63.37 ± 10.10 0.64
Body mass index (kg/m2) 25.90 ± 4.08 26.26 ± 3.72 26.42 ± 3.49 0.61 26.02 ± 3.63 26.45 ± 3.77 26.17 ± 4.25 0.58
Male, n (%) 61 (66.30 %) 88 (51.16 %) 67 (65.05 %) 0.02 107 (59.44 %) 91 (59.87 %) 18 (51.43 %) 0.64
Hypertension, n (%) 22 (23.91 %) 43 (25.0 %) 31 (30.10 %) 0.55 50 (27.78 %) 37 (24.34 %) 9 (25.72 %) 0.77
Hyperlipidemia, n (%) 16 (17.39 %) 27 (15.70 %) 29 (28.15 %) 0.03 26 (14.45 %) 22 (14.47 %) 10 (28.75 %) 0.09
Diabetes mellitus, n (%) 14 (15.22 %) 20 (11.62 %) 25 (24.27 %) 0.02 30 (16.67 %) 23 (15.13 %) 6 (17.14 %) 0.92
Current Smokers, n (%) 47 (51.08 %) 86 (50.0 %) 49 (47.57 %) 0.88 86 (47.78 %) 78 (51.32 %) 18 (51.43 %) 0.79
Plasma glucose (mmol/l) 5.71 ± 3.68 5.25 ± 2.26 5.62 ± 2.15 0.33 5.70 ± 3.27 5.24 ± 2.51 5.22 ± 2.68 0.32
LDL cholesterol (mmol/l) 2.52 ± 1.09 2.46 ± 1.02 2.48 ± 1.08 0.91 2.68 ± 1.03 2.42 ± 0.89 2.73 ± 1.13 0.04
Triglycerides (mmol/l) 1.57 ± 0.66 1.63 ± 0.70 1.66 ± 0.63 0.64 1.65 ± 0.58 1.64 ± 0.74 1.67 ± 0.66 0.97
HDL cholesterol (mmol/l) 1.32 ± 0.72 1.45 ± 0.74 1.30 ± 0.69 0.18 1.30 ± 0.75 1.40 ± 0.71 1.32 ± 0.72 0.52
CRP (mg/l) 1.50 ± 0.34 1.61 ± 0.44 1.58 ± 0.46 0.13 1.80 ± 0.53 1.73 ± 0.38 1.87 ± 0.66 0.22
Non enzymatic antioxidant parameters
 Uric Acid (µmol/l) 323.13 ± 120.6 313.69 ± 108.9 314.83 ± 132.6 0.82 319.4 ± 123.7 329.5 ± 123.5 323.1 ± 120.5 0.76
 Total bilirubin (µmol/l) 14.12 ± 6.57 13.32 ± 6.52 13.16 ± 7.20 0.56 12.88 ± 6.90 13.50 ± 6.70 13.07 ± 6.32 0.71
 Direct bilirubin (µmol/l) 5.34 ± 2.39 5.91 ± 2.09 5.53 ± 2.25 0.11 5.16 ± 2.14 5.37 ± 2.02 4.77 ± 2.71 0.28
 Albumin (g/l) 42.46 ± 6.28 43.06 ± 4.47 41.88 ± 7.33 0.3 40.89 ± 5.99 41.44 ± 4.65 43.15 ± 10.47 0.14
 Iron (µmol/l) 18.35 ± 5.07 17.34 ± 5.37 18.34 ± 6.32 0.23 18.58 ± 5.65 17.33 ± 4.91 18.07 ± 7.10 0.12
Enzymatic antioxidant parameters
 SOD activity (U/gHb) 1392.6 ± 219.3 1285.3 ± 188.9 979.4 ± 220.4 <10 −4
 GPx activity (U/gHb) 40.22 ± 12.79 42.91 ± 13.17 39.01 ± 11.97 0.1
 TAS (mmol/l) 1.51 ± 0.27 1.53 ± 0.31 1.42 ± 0.33 0.006 1.54 ± 0.29 1.50 ± 0.28 1.41 ± 0.35 0.002
  1. *P < 0.05 was required for statistical significance