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Fig. 3 | Biological Research

Fig. 3

From: The p. N103K mutation of leptin (LEP) gene and severe early onset obesity in Pakistan

Fig. 3

Pedigree of the Propositus. I-1: Proband’s deceased maternal grandmother. I-2: Proband’s deceased maternal grandfather. I-3: Proband’s deceased paternal grandfather (reported as obese by proband’s father, genotype not available). I-4: Proband’s deceased paternal grandmother (reported as overweight by proband’s father, genotype not available). II-5: Proband’s normal weight mother (BMI: 23.9 kg/m2, genotype CA). II-6: Proband’s normal weight mother (BMI: 26.5 kg/m2, genotype CA). III-6, 7: Proband’s normal weight sisters (BMI < 22 kg/m2, genotype CC). III-8: Proband’s overweight elder brother (BMI: 27.2 kg/m2, genotype CA). III-9: Proband, age of onset: 10 (BMI: 48.44 kg/m2, genotype AA)

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