Table 1 Anti-tumor activity of various samples of Rumex hastatus
Samples | Concentrations (µg/ml) | Average inhibition (mean ± SEM) | Percent inhibition (mean ± SEM) | IC50 (µg/ml) |
|---|---|---|---|---|
Rh.Cr | 1000 | 25.7 ± 0.3 | 85.5 ± 1.1*** | 197.9 |
500 | 19.0 ± 0.6 | 63.3 ± 1.9*** | ||
250 | 16.0 ± 1.2 | 53.3 ± 3.8*** | ||
125 | 13.3 ± 0.3 | 44.4 ± 1.1*** | ||
62.5 | 12.0 ± 0.0 | 40.0 ± 0.0*** | ||
31.25 | 10.0 ± 0.6 | 33.3 ± 1.9*** | ||
Rh.Hex | 1000 | 19.0 ± 0.6 | 63.3 ± 1.9*** | 395.1 |
500 | 16.3 ± 0.3 | 54.4 ± 1.1*** | ||
250 | 12.7 ± 0.3 | 42.2 ± 1.1*** | ||
125 | 11.0 ± 1.2 | 36.7 ± 3.8*** | ||
62.5 | 10.7 ± 0.3 | 35.5 ± 1.1*** | ||
31.25 | 08.0 ± 0.0 | 26.7 ± 0.0*** | ||
Rh.Chf | 1000 | 26.0 ± 1.2 | 86.7 ± 3.8* | 31.6 |
500 | 23.3 ± 0.3 | 77.8 ± 1.1** | ||
250 | 21.0 ± 0.0 | 70.0 ± 0.0*** | ||
125 | 19.7 ± 0.3 | 65.5 ± 1.1** | ||
62.5 | 17.7 ± 0.7 | 58.9 ± 2.2*** | ||
31.25 | 15.0 ± 0.6 | 50.0 ± 1.9*** | ||
Rh.EtAc | 1000 | 24.0 ± 0.6 | 80.0 ± 1.9** | 62.5 |
500 | 19.7 ± 0.7 | 65.5 ± 2.2*** | ||
250 | 18.0 ± 0.6 | 60.0 ± 1.9*** | ||
125 | 16.0 ± 1.2 | 53.3 ± 3.8*** | ||
62.5 | 15.0 ± 0.0 | 50.0 ± 0.0*** | ||
31.25 | 13.0 ± 1.2 | 43.3 ± 3.8*** | ||
Rh.Aq | 1000 | 14.0 ± 0.0 | 46.7 ± 0.0*** | 1138.9 |
500 | 12.6 ± 0.3 | 42.2 ± 1.1*** | ||
250 | 11.6 ± 0.3 | 38.9 ± 1.1*** | ||
125 | 09.0 ± 0.6 | 30.0 ± 1.9*** | ||
62.5 | 08.7 ± 0.3 | 28.9 ± 1.1*** | ||
31.25 | 05.3 ± 0.3 | 17.8 ± 1.1*** | ||
Rh.Sp | 1000 | 28.0 ± 0.0 | 93.3 ± 0.0ns | 18.1 |
500 | 25.0 ± 0.6 | 83.3 ± 1.9* | ||
250 | 23.7 ± 0.3 | 78.9 ± 1.1* | ||
125 | 19.0 ± 0.6 | 63.3 ± 1.9** | ||
62.5 | 17.0 ± 1.2 | 56.7 ± 3.9*** | ||
31.25 | 16.0 ± 0.0 | 53.3 ± 0.0** |