Fig. 5
From: Shenhua Tablet inhibits mesangial cell proliferation in rats with chronic anti-Thy-1 nephritis
Shenhua Tablet downregulates p-Erk1/2 and cyclin D1 while upregulating p21 in the renal cortex of rats with anti-Thy-1 nephritis. a Western blot was performed to detect the expression levels of p-Erk1/2, cyclin D1 and p21 in all drug-treated groups as well as the controls. b Quantification of the cyclin D1, p21 and p-Erk1/2. Expression level of p-Erk1/2 was normalized with total Erk1/2 while cyclin D1 and p21 were normalized with beta-actin. Each bar represents the mean ± SD of six rats. * p< 0.05, ** p< 0.01 vs. Thy-1; # p< 0.05, ## p< 0.01 vs. Irb group