TY - JOUR AU - Geng, Wenjia AU - Wei, Ribao AU - Liu, Shuwen AU - Tang, Li AU - Zhu, Hanyu AU - Chen, Pu AU - Wu, Jie AU - Zhang, Xueguang AU - Zhu, Fei AU - Yin, Zhong AU - Chen, Xiangmei PY - 2016 DA - 2016/03/11 TI - Shenhua Tablet inhibits mesangial cell proliferation in rats with chronic anti-Thy-1 nephritis JO - Biological Research SP - 17 VL - 49 IS - 1 AB - In China, mesangial proliferative glomerulonephritis (MsPGN) is one of the most common kidney diseases. In this study, we treated a rat model of chronic anti-Thy-1 MsPGN with Shenhua Tablet and evaluated whether the tablet was able to protect the kidney function. Thirty-six Wistar rats were randomly divided into six groups: (1) Sham surgery (Sham); (2) anti-Thy-1 nephritis model (Thy-1); (3) anti-Thy-1 nephritis model + irbesartan-treated (Irb); (4) anti-Thy-1 nephritis model + low-dose of Shenhua Tablet (SHL); (5) anti-Thy-1 nephritis model + medium-dose of Shenhua Tablet (SHM); (6) anti-Thy-1 nephritis model + high-dose of Shenhua Tablet (SHH). SN - 0717-6287 UR - https://doi.org/10.1186/s40659-016-0078-3 DO - 10.1186/s40659-016-0078-3 ID - Geng2016 ER -