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Table 3 GO functional and KEGG pathway enrichment analysis on genes in co-expression modules

From: Identification of novel gene and pathway targets for human epilepsy treatment

ID Term Description Count p value
Up-co-expression GOTERM_BP_FAT GO:0016310 ~ phosphorylation 5 0.023081277
GOTERM_BP_FAT GO:0006793 ~ phosphorus metabolic process 5 0.043264378
GOTERM_BP_FAT GO:0006796 ~ phosphate metabolic process 5 0.043264378
GOTERM_BP_FAT GO:0006915 ~ apoptosis 4 0.049975204
GOTERM_BP_FAT GO:0006814 ~ sodium ion transport 3 0.014081453
GOTERM_CC_FAT GO:0005886 ~ plasma membrane 11 0.02927495
GOTERM_CC_FAT GO:0044459 ~ plasma membrane part 8 0.033090626
GOTERM_MF_FAT GO:0030695 ~ GTPase regulator activity 4 0.020009788
GOTERM_MF_FAT GO:0060589 ~ nucleoside-triphosphatase regulator activity 4 0.021203692
GOTERM_MF_FAT GO:0008289 ~ lipid binding 4 0.02652355
GOTERM_MF_FAT GO:0031402 ~ sodium ion binding 3 0.012457524
GOTERM_MF_FAT GO:0005543 ~ phospholipid binding 3 0.027145214
Down-co-expression GOTERM_BP_FAT GO:0006955 ~ immune response 9 1.01E−07
GOTERM_BP_FAT GO:0050778 ~ positive regulation of immune response 6 2.45E−07
GOTERM_BP_FAT GO:0048584 ~ positive regulation of response to stimulus 6 2.73E−06
GOTERM_BP_FAT GO:0002684 ~ positive regulation of immune system process 6 2.84E−06
GOTERM_BP_FAT GO:0006952 ~ defense response 6 2.72E−04
GOTERM_MF_FAT GO:0048154 ~ S100 beta binding 2 0.003999687
GOTERM_MF_FAT GO:0048306 ~ calcium-dependent protein binding 2 0.031586688
GOTERM_MF_FAT GO:0042803 ~ protein homodimerization activity 3 0.042687029
GOTERM_MF_FAT GO:0004175 ~ endopeptidase activity 3 0.052602322
GOTERM_MF_FAT GO:0005509 ~ calcium ion binding 4 0.05926993
GOTERM_CC_FAT GO:0005576 ~ extracellular region 7 0.020898219
KEGG_PATHWAY hsa04610:Complement and coagulation cascades 3 0.003647135
KEGG_PATHWAY hsa04612:Antigen processing and presentation 3 0.005241774
KEGG_PATHWAY hsa05322:Systemic lupus erythematosus 3 0.007393725
  1. Count represents the gene number