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Fig. 1 | Biological Research

Fig. 1

From: Functional disruption of human leukocyte antigen II in human embryonic stem cell

Fig. 1

Disruption of CIITA in hESCs by TALENs. a Sequences on exon 2 of human CIITA for target by TALENs.b Alignment of the genomic sequences of mutants and wildtypes (wt) at the TALEN target site. The number of deleted (dashes) or inserted (letters in red) nucleotides compared with the wt sequences is indicated on the left of each sequence. c Efficiency of generation CIITA-deficient hESCs using TALENs in X1

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