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Table 2 Acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii and reference compound (galantamine)

From: Cytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae)

Compounds Concentration (µg/mL) % AChE inhibition IC50 (µg/mL)
1 50 94.33 ± 8.15 19.13 ± 0.41a
25 71.67 ± 6.03
12.5 18.00 ± 8.89
6.25 28.00 ± 6.56
2 50 82.67 ± 7.04 34.15 ± 1.66b
25 67.00 ± 4.36
12.5 47.33 ± 2.08
6.25 14.00 ± 6.00
3 50 87.00 ± 8.74 45.69 ± 3.65c
25 70.67 ± 3.50
12.5 31.67 ± 5.20
6.25 30.33 ± 3.51
Galantamine 20 83.00 ± 8.89 8.22 ± 2.73d
5 69.67 ± 4.16
2 57.67 ± 4.04
0.5 38.00 ± 1.00
  1. Values with different letters are significantly different at p < 0.05
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