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Table 1 Synergistic effect of ZALE combined with different drugs on HeLa cells analyzed by Jin’s formula (value listed in the table)

From: Anticancer properties and enhancement of therapeutic potential of cisplatin by leaf extract of Zanthoxylum armatum DC.

Chemotherapeutic drugs ZALE (15 ug/mL)
MMC 2.14
Cisplatin 1.85
CPT 1.85
  1. According to Jin’s formula,  < 0.85 indicates antagonism, 0.85 ≤  < 1.15 indicates additive effects, and  ≥ 1.15 indicates synergism