Figure 5
From: Suppression of miR-221 inhibits glioma cells proliferation and invasion via targeting SEMA3B
Knockdown endogenous SEMA3B reversed the effect of miR-221 Inhibitor. a Western blot showed SEMA3B level in a U87MG cells with SEMA3B gene stably silenced, b CCK-8 assay was employed to detect the cell proliferation in U87MG wild type and SEMA3B KD cells treated with scramble or miR-221 inhibitor (100 pM). Transwell assay without matrigel coated for testing cell migration (c) and transwell assay with matrigel coated was employed to detect the cell invasion ability (d) in U87MG cells treated with scramble or miR-221 inhibitor (100 pM). *p < 0.05; **p < 0.01.