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Table 1 Clinical and biochemical features of patients with ACS and controls subjects

From: Metabolic interactions between hyperhomocysteinemia and endothelin-1 among Tunisian patients with acute coronary diseases

 

Patients (n = 157)

Control subjects (n = 142)

P

Age (x ± σ years)

64.8 ± 11.7

56.8 ± 9.4

NS

Sex

 Men (%)

121 (77 %)

111 (78.2 %)

NS

 Women (%)

36 (23 %)

31 (21.8 %)

NS

BMI (kg /m2)

27.6 ± 4

23.3 ± 2.2

NS

Hypertension (%)

88

0

-

Obesity (%)

52

8.5 %

-

Diabetes (%)

64

0

-

Smoking (%)

62.4

7

-

Family cardiac history (%)

68

6

-

Personnel cardiac history (%)

66

0

-

Post menopausal women (%)

100

82

-

Dyslipidemia (%)

40

0

-

Sedentary (%)

43

11

-

Alcohol (%)

33

14

-

Glucose (x ± σ mmolL/)

9.8 ± 4.2

5.40 ± 0.84

<0.0001

TC (x ± σ mmol/L)

5.70 ± 3.1

4.60 ± 2.6

<0.001

HDL-C (x ± σ mmol/L)

1.14 ± 0.22

1.30 ± 0.41

NS

LDL-C (x ± σ mmol/L)

3.60 ± 2.16

2.80 ± 1.4

<0.001

TG (x ± σ mmol/L)

1.60 ± 0.9

1.24 ± 0.3

NS

ApoA1 (x ± σ. g/L)

1.41 ± 0.62

1.80 ± 0.2

<0.00001

ApoB (x ± σ. g/L)

1.40 ± 0.81

0.70 ± 0.2

<0.00001

Treatment

 ACA-1 inhibitors (%)

97

0

-

 Statins (%)

38

0

-

 Beta-Blokers (%)

33

0

-

 Ca-Blokers (%)

27

0

-

 Diuretics (%)

17

0

-

  1. ApoA apolipoprotein A, ApoB apolipoprotein B, BMI body mass index, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, x mean, σ standard deviation, NS not significant