|
Gain phenotype
|
Gain phenotype
| |
L-Arginine
|
50
|
75
|
C-Source, carboxylic acid
|
His-Met
|
61
|
56
|
N-Source, peptide
|
Carbenicillin
|
158
|
71
|
Wall, lactam
|
Cefsulodin
|
80
|
80
|
Wall, cephalosporin
|
Ruthenium red
|
78
|
110
|
Respiration, mitochondrial Ca2+ porter
|
Erythromycin
|
67
|
80
|
Protein synthesis, 50S ribosomal subunit, macrolide
|
|
Lost phenotype
|
Lost phenotype
| |
D-Gluconic acid
|
−112
|
−106
|
C-Source, carboxylic acid
|
D-Mannitol
|
−68
|
−57
|
C-Source, carbohydrate
|
L-Valine
|
−60
|
−58
|
N-Source, amino acid
|
L-Methionine Sulfone
|
−69
|
−95
|
S-Source, organic
|
Orphenadrine
|
−78
|
−146
|
Anti-cholinergic
|
Patulin
|
−534
|
−495
|
Microtubulin polymerization inhibitor, antifungal
|
2,2′-Dipyridyl
|
−401
|
−397
|
Chelator, lipophilic
|
Sodium Arsenite
|
−332
|
−242
|
Toxic anion
|
Sodium Arsenate
|
−305
|
−321
|
Toxic anion, P04 analog
|
Dichlofluanid
|
−271
|
−119
|
Fungicide, phenylsulphamide
|
Thiamphenicol
|
−269
|
−193
|
Protein synthesis, amphenicol
|
Chloramphenicol
|
−209
|
−173
|
Protein synthesis, amphenicol
|
Chlorodinitrobenzene
|
−182
|
−187
|
Oxidizes sulfhydryls, depletes glutathione
|
8-Hydroxyquinoline
|
−181
|
−230
|
Chelator, lipophilic
|
Nafcillin
|
−163
|
−172
|
Wall, lactam
|
Antimony (III) chloride
|
−158
|
−153
|
Toxic cation
|
1,10-Phenanthroline monohydrate
|
−152
|
−171
|
Chelator, lipophilic
|
Captan
|
−152
|
−113
|
Fungicide, carbamate
|
Sulfathiazole
|
−148
|
−172
|
Folate antagonist, PABA analog
|
Gallic acid
|
−141
|
−115
|
Respiration, ionophore, H+
|
Poly-L-lysine
|
−140
|
−63
|
Membrane, detergent, cationic
|
Protamine sulfate
|
−129
|
−109
|
Membrane, nonspecific binding
|
Sulfadiazine
|
−127
|
−107
|
Folate antagonist, PABA analog
|
Oxacillin
|
−124
|
−130
|
Wall, lactam
|
Myricetin
|
−113
|
−122
|
DNA & RNA synthesis, polymerase inhibitor
|
Nickel chloride
|
−113
|
−80
|
Toxic cation
|
Plumbagin
|
−106
|
−118
|
Oxidizing agent
|
Oxophenylarsine
|
−99
|
−161
|
Tyrosine phosphatase inhibitor
|
trans-Cinnamic acid
|
−98
|
−90
|
Respiration, ionophore, H+
|
EDTA
|
−67
|
−88
|
Chelator, hydrophilic
|
Glycine hydroxamate
|
−66
|
−136
|
tRNA synthetase
|