|
Samples
|
Concentrations (
μ
g/mL)
|
Percent Inhibition (AChE)
|
AChE IC
50
(
μ
g/mL)
|
Percent inhibition (BChE)
|
BChE IC
50
(
μ
g/mL)
|
|---|
|
Al.MeF
|
1000
|
78.65 ± 0.70***
|
280
|
82.68 ± 0.60***
|
220
|
|
500
|
67.25 ± 0.55***
| |
69.42 ± 0.60***
|
|
250
|
47.21 ± 0.62***
| |
52.51 ± 0.66***
|
|
125
|
31.55 ± 0.56***
| |
41.27 ± 0.62***
|
|
Al.HxF
|
1000
|
72.51 ± 0.62***
| |
64.36 ± 0.61***
|
400
|
|
500
|
63.44 ± 0.44***
|
310
|
53.40 ± 0.52***
|
|
250
|
42.46 ± 0.47***
| |
39.46 ± 0.60***
|
|
125
|
23.68 ± 0.64***
| |
22.52 ± 0.49***
|
|
Al.CfF
|
1000
|
67.42 ± 0.46 ***
| |
83.49 ± 0.46***
|
160
|
|
500
|
53.53 ± 0.41***
|
390
|
72.48 ± 0.50***
|
|
250
|
40.62 ± 0.69***
| |
59.59 ± 0.66***
|
|
125
|
18.46 ± 0.67***
| |
45.57 ± 0.63***
|
|
Al.EaF
|
1000
|
77.45 ± 0.55 ***
| |
74.41 ± 0.60***
|
260
|
|
500
|
57.63 ± 0.64***
|
270
|
61.53 ± 0.71***
|
|
250
|
48.45 ± 0.66 ***
| |
49.45 ± 0.77***
|
|
125
|
36.36 ± 0.50***
| |
31.75 ± 0.58***
|
|
Al.WtF
|
1000
|
72.44 ± 0.58***
| |
78.62 ± 0.36***
|
210
|
|
500
|
60.51 ± 0.59***
|
263
|
69.22 ± 0.47***
|
|
250
|
48.62 ± 0.70***
| |
52.52 ± 0.71***
|
|
125
|
31.47 ± 0.55***
| |
43.52 ± 0.70***
|
|
Al.SPF
|
1000
|
84.36 ± 0.64 ***
| |
80.37 ± 0.54***
|
120
|
|
500
|
77.34 ± 0.65***
|
90
|
73.44 ± 0.50***
|
|
250
|
65.58 ± 0.67***
| |
62.51 ± 0.72***
|
|
125
|
53.60 ± 0.50***
| |
49.28 ± 0.61***
|
|
Al.FLVF
|
1000
|
88.31 ± 0.57ns
| |
85.46 ± 0.62***
|
100
|
|
500
|
79.46 ± 0.63 *
|
70
|
76.58 ± 0.69***
|
|
250
|
67.53 ± 0.49 ***
| |
65.68 ± 0.42***
|
|
125
|
59.38 ± 0.50ns
| |
52.46 ± 0.72***
|
|
Galanthamine
|
1000
|
91.37 ± 0.65
| |
94.50 ± 0.71
|
47
|
|
500
|
83.33 ± 0.55
|
52
|
85.47 ± 0.59
|
|
250
|
73.31 ± 0.60
| |
71.72 ± 0.51
|
|
125
|
61.32 ± 0.54
| |
65.37 ± 0.69
|
- Result expressed as % inhibition (mean ± SEM of n = 3) and IC50 values. Values significantly different as compared to positive control, *:P < 0.05, ***:P < 0.001, ns: P >0.05.
