Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L.: potential effectiveness in Alzheimer’s and other neurological disorders

Table 2 Results of antioxidant potential of Atriplex laciniata against DPPH and ABTS free Radicals using ascorbic acid as standard

Samples	Conc. (μ g/mL)	DPPH Percent inhibition	DPPH IC ₅₀ (μ g/mL)	ABTS Percent inhibition	ABTS IC ₅₀ (μ g/mL)
Al.MeF	1000	83.23 ± 0.44^**	82	81.49 ± 0.60^***	70
	500	79.50 ± 0.61 ^ns		75.45 ± 0.59^**
	250	68.47 ± 0.46^***		64.52 ± 0.60^***
	125	53.47 ± 0.70^***		57.58 ± 0.57^***
Al.HxF	1000	65.57 ± 0.43^***	270	69.90 ± 1.04 ^***	215
	500	58.12 ± 0.94^***		61.53 ± 0.65^***
	250	48.76 ± 1.09^***		52.20 ± 1.04^***
	125	34.38 ± 0.50^***		40.50 ± 0.73^***
Al.CfF	1000	74.50 ± 0.56^***	210	83.42 ± 0.57^***	190
	500	61.40 ± 0.55^***		72.32 ± 0.52^***
	250	52.36 ± 0.57^***		58.27 ± 0.57^***
	125	43.30 ± 0.52^***		37.30 ± 0.64^***
Al.EaF	1000	69.37 ± 0.58^***	382	76.34 ± 0.63^***	360
	500	62.29 ± 0.43^***		67.54 ± 0.46^***
	250	24.58 ± 0.56^***		33.48 ± 0.60^***
	125	17.39 ± 0.60^***		28.52 ± 0.66^***
Al.WtF	1000	67.83 ± 1.07^***	210	69.37 ± 1.10^***	310
	500	61.56 ± 0.69^***		57.56 ± 0.45^***
	250	52.48 ± 0.54^***		46.36 ± 0.55^***
	125	40.90 ± 1.16^***		35.57 ± 0.84^***
Al.SPF	1000	83.37 ± 0.52^**	83	78.40 ± 0.51^***	92
	500	73.38 ± 0.76^***		71.44 ± 0.55^***
	250	67.24 ± 0.80^***		63.47 ± 0.52^***
	125	54.40 ± 0.76^***		52.39 ± 0.49^***
Al.FLVF	1000	89.41 ± 0.55 ^ns	33	90.34 ± 0.55 ^ns	30
	500	83.27 ± 0.58 ^ns		86.36 ± 0.49^***
	250	76.35 ± 0.51 ^ns		73.52 ± 0.62 ^ns
	125	63.28 ± 0.57 ^*		67.42 ± 0.55 ^ns
Ascorbic Acid	1000	87.90 ± 0.96	14	89.30 ± 0.61	37
	500	83.08 ± 0.47		80.37 ± 0.54
	250	79.85 ± 2.24		73.37 ± 0.64
	125	67.36 ± 0.57		64.45 ± 0.65

Values significantly different as compared to positive control, *:P < 0.05, **:P < 0.01, ***:P < 0.001, ns: P >0.05. Values expressed as Percent inhibition (Mean ± SEM of n = 3) and IC₅₀.

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