Antioxidant and anticholinesterase investigations of Rumex hastatus D. Don: potential effectiveness in oxidative stress and neurological disorders

Table 1 Percent AChE and BChE inhibition potential of various samples of Rumex hastatus

Samples	Concentrations (μg/mL)	Percent	AChEI	Percent	BChEI
		AChEI	IC ₅₀	BChEI	IC ₅₀
		(mean ± S.E.M)	(μg/mL)	(mean ± S.E.M)	(μg/mL)
Rh.Cr	1000	65.33 ± 0.49^***		69.58 ± 1.12^***
	500	59.03 ± 0.23^***	218	63.65 ± 1.34^***	265
	250	52.03 ± 0.48^***		49.31 ± 2.15^***
	125	39.00 ± 0.58^***		41.03 ± 0.48^***
Rh. Hex	1000	42.67 ± 0.89^***		51.44 ± 0.58^***
	500	39.00 ± 1.15^***	1420	46.90 ± 0.96^***	890
	250	38.00 ± 0.00^***		39.28 ± 2.19^***
	125	29.03 ± 0.23^***		32.70 ± 1.60^***
Rh. Chf	1000	76.70 ± 1.60^***		75.76 ± 0.71^***
	500	71.73 ± 0.78^***	75	65.65 ± 1.32^***	92
	250	68.70 ± 1.60^***		61.23 ± 1.83^***
	125	52.90 ± 0.52^***		53.13 ± 0.20^***
Rh. EtAc	1000	77.23 ± 0.40^***		74.56 ± 1.06^***
	500	69.90 ± 0.43^***	115	66.42 ± 0.43^***	115
	250	55.90 ± 0.20^***		59.42 ± 0.46^***
	125	51.13 ± 0.20^***		51.87 ± 1.27^***
Rh.Aq	1000	46.20 ± 0.23^***		61.03 ± 0.35^***
	500	38.80 ± 0.37^***	1210	52.08 ± 0.47^***	220
	250	37.90 ± 0.48^***		51.91 ± 0.88^***
	125	31.74 ± 0.68^***		44.90 ± 0.96^***
Rh.Sp	1000	81.67 ± 0.88^***		77.52 ± 3.28^***
	500	72.87 ± 1.27^***	135	63.93 ± 0.67^***	165
	250	60.95 ± 2.01^***		61.83 ± 1.21^***
	125	49.08 ± 1.04^***		42.22 ± 1.28^***
Rh.Fl	1000	91.62 ± 1.67^**		79.16 ± 0.86^***
	500	84.76 ± 0.61^***	20	77.98 ± 0.72^***	175
	250	81.03 ± 0.86 ^ns		59.65 ± 0.98^***
	125	67.70 ± 0.92 ^ns		41.93 ± 1.01^***
Gal	1000	96.00 ± 0.30		88.61 ± 0.43
	500	91.26 ± 1.27	20	83.25 ± 1.40	47
	250	82.91 ± 1.30		74.03 ± 0.86
	125	69.91 ± 0.89		61.22 ± 1.28

Data is represented as mean ± S.E.M; n = 3, * represent level of significance like; * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
Gal : Galanthamine.

ISSN: 0717-6287