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Table 3 Effect of berberine on liver glutathione, catalase and superoxide dismutase in male mice infected with S. mansoni

From: Role of berberine in ameliorating Schistosoma mansoni-induced hepatic injury in mice

Experimental groups GSH CAT SOD
(mmol/g liver) (U/g liver) (U/g liver)
Control 0.8 ± 0.02 1.3 ± 0.04 1455 ± 8.5
PZQ 1.1 ± 0.02a 1.4 ± 0.04 1371 ± 1.4a
BER 1.2 ± 0.02a 1.6 ± 0.01a 1589 ± 6.2ab
Infected 0.61 ± 0.02a 0.75 ± 0.02a 859 ± 1.3a
Infected + PZQ 0.76 ± 0.08ab 1.3 ± 0.01bc 902 ± 2.2abc
Infected + BER 0.67 ± 0.02ab 1.2 ± 0.03bc 924 ± 1.7abc
  1. Values are means ± SD (n = 8). aSignificant difference as compared with Group I (p ≤ 0.05). bSignificant difference as compared with corresponding control group (p ≤ 0.05). cSignificant difference as compared with infected group (Group IV) (p ≤ 0.05).
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