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Table 2 Effect of berberine chloride on hepatic ALT, AST, ALP and γGT in male mice infected with S. mansoni

From: Role of berberine in ameliorating Schistosoma mansoni-induced hepatic injury in mice

Experimental groups

ALT

AST

ALP

γ-GT

(U/g)

(U/g)

(U/g)

(U/g)

Control

304 ± 1.8

229 ± 1.8

16 ± 1

25 ± 0.8

PZQ

315 ± 1.7a

220 ± 4.5a

13 ± 0.3a

18 ± 1a

BER

318 ± 1.4a

255 ± 2.3a

7.4 ± 0.4a

15 ± 0.8a

Infected

218 ± 3.6a

125 ± 1a

36 ± 1.2a

48 ± 1.6a

Infected + PZQ

263 ± 1.3abc

146 ± 1.9 abc

17 ± 1bc

16 ± 0.5ac

Infected + BER

280 ± 2.8abc

182 ± 2.4abc

12 ± 1.6abc

20 ± 0.6abc

  1. Values are means ± SD (n = 8). aSignificant difference as compared with Group I (p ≤ 0.05). bSignificant difference as compared with corresponding control group (p ≤ 0.05). cSignificant difference as compared with infected group (Group IV) (p ≤ 0.05).