Effects of different treatments on Cyclin D1, Bcl-2 and Survivin mRNA expression in Hep3B cells. The mRNA levels of Cyclin D1 (A), Bcl-2 (B) and Survivin (C) in Hep3B cells were determined by Real-time qRT-PCR after 72 hours of siRNA transfection. The mRNA expression of these genes was normalized with β-actin. Values were given as mean value ± standard deviation (SD) of triplicate. **p < 0.01, *p < 0.05 compared to untreated cell group and ##p < 0.01, #p < 0.05 compared to siRNA cocktail treated cell group.