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Table 2 Relationship between White Light Bronchoscopy (WLB) (A), Autofluorescence Broncoscopy (AFB) (B) and Histopathology Assay (HA)

From: Biomarkers for screening of lung cancer and pre-neoplastic lesions in a high risk Chilean population

A

HA % (N)

Variable % (N)

WLB % (N)

Normal

Inflammation

Hyperplasia

Metaplasia

Dysplasia

LC

Normal

23.47 (23)

17.39 (4)

4.35 (1)

56.52 (13)

21.74 (5)

0

0

Inflammation (a)

61.22 (60)

11.67 (7)

28.33 (17)

48.33 (29)

6.67 (4)

5.0 (3)

0

Suspicious (b)

3.06 (3)

0

100 (3)

0

0

 

0

LC

12.25 (12)

0

0

0

0

25.0 (3)

75.0 (9)

TOTAL

(98)

(11)

(21)

(42)

(9)

(6)

(9)

B

HA% (N)

Variable % (N)

AFB % (N)

Normal

Inflammation

Hyperplasia

Metaplasia

Dysplasia

LC

Normal

18.36 (18)

22.22 (4)

5.56 (1)

61.11 (11)

11.11 (2)

0

0

Inflammation (a)

57.14 (56)

12.5 (7)

30.35 (17)

50.0 (28)

5.36 (3)

1.79 (1)

0

Suspicious (b)

12.25 (12)

0

25.0 (3)

25.0 (3)

33.33 (4)

16.67 (2)

0

LC

12.25 (12)

0

0

0

0

25.0 (3)

75.0 (9)

TOTAL

98

11

21

42

9

6

9

  1. (a): Abnormal or Inflammation (Erythema, swelling or thickening of bronchial mucosa, airway inflammation, and Fibrosis) [31].
  2. (b): Suspicious for pre invasive or preneoplastic lesion for AFB and cancer in situ (CIS) for WLB.