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Table 2 Relationship between White Light Bronchoscopy (WLB) (A), Autofluorescence Broncoscopy (AFB) (B) and Histopathology Assay (HA)

From: Biomarkers for screening of lung cancer and pre-neoplastic lesions in a high risk Chilean population

A HA % (N)
Variable % (N) WLB % (N) Normal Inflammation Hyperplasia Metaplasia Dysplasia LC
Normal 23.47 (23) 17.39 (4) 4.35 (1) 56.52 (13) 21.74 (5) 0 0
Inflammation (a) 61.22 (60) 11.67 (7) 28.33 (17) 48.33 (29) 6.67 (4) 5.0 (3) 0
Suspicious (b) 3.06 (3) 0 100 (3) 0 0   0
LC 12.25 (12) 0 0 0 0 25.0 (3) 75.0 (9)
TOTAL (98) (11) (21) (42) (9) (6) (9)
B HA% (N)
Variable % (N) AFB % (N) Normal Inflammation Hyperplasia Metaplasia Dysplasia LC
Normal 18.36 (18) 22.22 (4) 5.56 (1) 61.11 (11) 11.11 (2) 0 0
Inflammation (a) 57.14 (56) 12.5 (7) 30.35 (17) 50.0 (28) 5.36 (3) 1.79 (1) 0
Suspicious (b) 12.25 (12) 0 25.0 (3) 25.0 (3) 33.33 (4) 16.67 (2) 0
LC 12.25 (12) 0 0 0 0 25.0 (3) 75.0 (9)
TOTAL 98 11 21 42 9 6 9
  1. (a): Abnormal or Inflammation (Erythema, swelling or thickening of bronchial mucosa, airway inflammation, and Fibrosis) [31].
  2. (b): Suspicious for pre invasive or preneoplastic lesion for AFB and cancer in situ (CIS) for WLB.